Diabetes Medications

Diabetes Medications
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Diabetes Medications

An overview of the classes, mechanisms, indications, and side effects of diabetes medications, including metformin, SGLT2 inhibitors, GLP-1 receptor antagonists, DPP4 inhibitors, and sulfonylureas. Pdf of slides available for download here: https://drive.google.com/drive/folders/0B9SDUwepGWeUTmtscnJSSjR5OE0

Summary of 2017 ADA Guidelines: https://emedicine.medscape.com/article/117853-guidelines

Complete 2018 ADA Guidelines: https://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf

Summary of AACE Guidelines: https://www.aace.com/disease-state-resources/diabetes/depth-information/glycemic-management-type-2-diabetes

Strong Medicine video on the Normal Physiology of Insulin and Glucagon: https://www.youtube.com/watch?v=-3J6QRMerQE

#diabetes #diabetic #hyperglycemia
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20 Comments

  1. Strong Medicine

    In the video, I mention that the algorithm presented is "generally" consistent with ADA and AACE guidelines. In short, the video algorithm recommends that lifestyle modifications can be initially tried alone for motivated patients whose A1c<7.5%; while ADA/AACE guidelines recommend anyone diagnosed with type 2 diabetes, no matter how near-normal their A1c is, should be placed on metformin. In other words, the implication is that there should be no such thing as "diet controlled diabetes". Other recommendations may use A1c cutoffs of 7.0%. Given that motivated individuals with newly diagnosed type 2 diabetes can bring down their A1c 1.0-2.0% with lifestyle modifications alone, and because I personally trend my practice towards keeping patient pill burden on the lower end, I don't personally recommend starting metformin at A1c levels < 7.5% IF the patient is motivated and otherwise able to enact major dietary changes. The argument against this (i.e. the argument to start every patient with type 2 diabetes on metformin) is that it's cheap and very safe, and that attempts to use lifestyle modifications alone is not successful for most patients. But I'm not convinced there is any benefit (EDIT: patient-centered benefit) to using metformin for those patients whose A1c could otherwise be successfully brought to their target A1c with diet/weight loss alone.

  2. jackie reinstedler

    Thank you!! Sharing with a family member:)

  3. Dareen Rose

    Thanks for sharing the information. I use the Ambrosia Blucon with Libre, It helps me to get constant readings on my Apple Watch and iPhone, the alarms help me at night. It is a much more reliable and accurate cgm with a low cost. I loved!

  4. Robert Smith

    Sorry but Metformin should be taken off the market. I for one never had the drug preform at all for me. I also know many people who have suffered though the same results. As far as I am concerned it should never be used. Too many people have either gone through constant sickness or months of frustration because of the drug and eventually ended up having to switch to a different medication all together.

  5. Anwar Ali

    Greetings Doctor
    I'm a 57yrsold longterm T2 diabetic.
    Was under Glimipiride 2 mg +Metformin 1gm+ INVOKANA 100 + LANTUS Glargine 16units.
    I stopped Glimipiride 2 mg after seeing some video. Hoping to get out of sulfunos.
    15 days now.
    But my fasting and daytime readings are constantly raised to 180 ave. Even while fasting twice a week.
    And I feel drowsy….
    Should I go back to Glimipiride 2mg?
    Thank you

  6. 당뇨 스토리. Diabetes Story.

    Visit what foods for made high and lower diabetes! May everyone escape from diabetes.

  7. V_ronyca

    Wow! Your videos are amazing. Thank you!

  8. malek khan

    Acca dayabetic metro pro name Kono osud ace ki

  9. sid adk

    Can a pt having hypothyroidism take metformin?

  10. abdullah saleh

    Dr Stronng ; Thaaaanks for you from Saui Arabia 🤚🏻 I am following your channel with great intrest … I cnseder you my best teacher 👌🌺🌹

  11. Ann Alcantara

    My high blood ano ang gmot .

  12. Ann Alcantara

    4years na ako take ng metformin

  13. Wittawat Kasayapanand

    Thank you very much Doctor Eric Strong, this is my third time, watching this video, and I seem to grasp thing I didn’t before. I did not watch medical video to take any particular examination, but I found ,that yours are the BEST in practical medicine, which I would never get if only I just read from textbook, or manual. I thank you for taking time to teach us , Doctors around the world. I would like to wish you and your family a very very Merry Christmas and a Happy New Year ! I have been listening your lectures for a little over the year , how time fly. 🙂

  14. Gisele Montigny

    great. thanks once more. I am learning with all your videos for a board certification test 🙂

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